Timely and relevant thoracic oncology news brought to you by the only global association dedicated to the multidisciplinary study of lung cancer.

Timely and relevant thoracic oncology news brought to you by the only global association dedicated to the multidisciplinary study of lung cancer.



  • Toward Durable Disease Control in EGFR-Mutant (mt) NSCLC: Interpreting the Survival Signals from FLAURA2 and MARIPOSA

    Toward Durable Disease Control in EGFR-Mutant (mt) NSCLC: Interpreting the Survival Signals from FLAURA2 and MARIPOSA

    By

    Ilit Turgeman, MD, et al.
    Evolving Standards of Care, Targeted Therapies

    While the FLAURA2 and MARIPOSA trials represent a defining step toward durable disease control in EGFR mt (+) NSCLC, Drs. Ilit Turgeman and Pasi A. Jänne emphasize that further advances will depend on understanding what persists after an initial response.


  • Research Points to Translational Path Toward Precision Immunotherapies for EGFR-Mutant NSCLC

    Research Points to Translational Path Toward Precision Immunotherapies for EGFR-Mutant NSCLC

    By

    Taylor Fithian
    Immuno-Biology, Systemic, Targeted, & Immune Therapies, Targeted Therapies

    Dr. Yongfeng He said recent data show EGFR-L858R to be a shared, druggable neoantigen and provide a compelling rationale for the development of mutation-directed immunotherapies.


  • Under Therapeutic Pressure: ELCC Session Highlights How Tumor Switching is Reshaping the Treatment Landscape

    Under Therapeutic Pressure: ELCC Session Highlights How Tumor Switching is Reshaping the Treatment Landscape

    By

    Haleigh Behrman
    Meeting News, Targeted Therapies, Tumor Biology

    Experts emphasize the need for multidisciplinary approaches, personalized therapies, and strategies to address intratumor heterogeneity.


  • Keynote Address Explores the Future of Biomarkers in the ADC Era

    Keynote Address Explores the Future of Biomarkers in the ADC Era

    By

    Haleigh Behrman
    Evolving Standards of Care, Meeting News, Targeted Therapies

    During his lecture at the 2026 European Lung Cancer Congress, Dr. Fred R. Hirsch outlined the current state of knowledge in ADC research, as well as what still needs to be learned.


  • Final Results From the ETOP ADEPPT Trial Show Promise for Two Underrepresented Patient Populations

    Final Results From the ETOP ADEPPT Trial Show Promise for Two Underrepresented Patient Populations

    By

    Haleigh Behrman
    Meeting News, Targeted Therapies

    The findings, presented by Dr. Jarushka Naidoo at ELCC 2026, demonstrated that treatment with adagrasib was effective in fit patients aged 70 years and older with KRAS G12C-mutant NSCLC and provided quality-of-life benefits for those with poor performance status.


  • Personalized Lung Cancer Therapies: One Size Does Not Fit All

    Personalized Lung Cancer Therapies: One Size Does Not Fit All

    By

    Haleigh Behrman
    Evolving Standards of Care, Meeting News, Targeted Therapies

    During the TTLC 2026 Opening Keynote, Dr. John V. Heymach said personalizing lung cancer therapies will require disentangling heterogeneity to understand the underlying factors driving the disease in each patient.


  • Debate Centers on Whether RAS Inhibitors Will Become First-Line Therapy by 2026

    Debate Centers on Whether RAS Inhibitors Will Become First-Line Therapy by 2026

    By

    Taylor Fithian
    Evolving Standards of Care, Meeting News, Targeted Therapies

    Drs. Ferdinandos Skoulidis and Marina C. Garassino went head-to-head over whether emerging KRAS combination data support first-line adoption by year’s end.


  • Research to Watch: Aumolertinib Delivers Notable Performance as an EGFR-Targeted Therapy in the Adjuvant Setting

    Research to Watch: Aumolertinib Delivers Notable Performance as an EGFR-Targeted Therapy in the Adjuvant Setting

    By

    Haleigh Behrman
    Evolving Standards of Care, Targeted Therapies

    Results from the phase III ARTS trial illustrate the potential of aumolertinib as adjuvant therapy for patients with resected EGFR-mutated NSCLC.


  • The Power of Team-Based Science

    The Power of Team-Based Science

    By

    Haleigh Behrman
    Names & News, Targeted Therapies

    After being awarded the $2.5 million IASLC-LCRF grant, ILCN follows up with the research progress of Dr. David Barbie and his international team of investigators.


  • Targeting NRG1 Fusions: A Potential Role for Zenocutuzumab as a First-Line Therapeutic Option

    Targeting NRG1 Fusions: A Potential Role for Zenocutuzumab as a First-Line Therapeutic Option

    By

    Taylor Fithian
    Evolving Standards of Care, Meeting News, Targeted Therapies

    Dr. Stephen Liu recently highlighted the safety and efficacy of a targeted therapy for patients with NRG1-positive cancers with updated data from the ongoing eNRGy trial.