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Home Evolving Standards of Care

Structure-Based Classification System for EGFR Mutations May Help Clinicians Personalize Treatments for More Patients

Xiuning Le, MD, PhD
+more
on: June 21, 2022In: Evolving Standards of Care
Structure-Based Classification System for EGFR Mutations May Help Clinicians Personalize Treatments for More Patients

Grouping mutations based on their likelihood of response to specific drug types in future EGFR TKI trials may eventually help physicians tailor treatments for patients with atypical mutations. Read more

More Robust Tools Needed to Predict who will Respond to Immune Checkpoint Inhibitors

Andrew McKenzie, PhD
on: June 21, 2022In: Evolving Standards of Care
More Robust Tools Needed to Predict who will Respond to Immune Checkpoint Inhibitors

Investigators at Sarah Cannon look to next-generation sequencing for molecular signatures that may correlate with response. Read more

Real-World Data from Taiwan Shows Stage Shift Has Improved Lung Cancer Survival Rates

Pan-Chyr Yang, MD, PhD
+more
on: June 07, 2022In: Evolving Standards of Care, Industry News & Regulatory Approvals
Real-World Data from Taiwan Shows Stage Shift Has Improved Lung Cancer Survival Rates

Researchers say increased screening of at-risk populations, including those who have never smoked, may improve survival more than any other strategy. Read more

Using Comparative Effectiveness Data Based on Non-Randomized Study Designs to Support Regulatory, Reimbursement Decision-Making

Sreeram Ramagopalan, PhD
on: June 07, 2022In: Evolving Standards of Care
Using Comparative Effectiveness Data Based on Non-Randomized Study Designs to Support Regulatory, Reimbursement Decision-Making

Study provides evidence to support the potential role of real-world data in consideration of technologies where only single-arm trial data exists. Read more

In Measuring Outcomes, a Longer-Term View May be Needed

Mark Hennon, MD
+more
on: June 07, 2022In: Evolving Standards of Care
In Measuring Outcomes, a Longer-Term View May be Needed

When publicly reported patient outcomes emerge, the data available to patients should paint the most complete picture possible. Read more


Alternative Dosing Strategies for Immune Checkpoint Inhibitors

Michiel Zietse, MSc
+more
on: May 24, 2022In: Evolving Standards of Care
Alternative Dosing Strategies for Immune Checkpoint Inhibitors

Combining fixed- and weight-based dosing approaches may reduce costs without compromising efficacy. Read more

Panel Explores Emerging Treatments and Sequencing Strategies for Patients with Advanced NSCLCs Driven by Rare Oncogenes

Beth Fand Incollingo
on: May 24, 2022In: Evolving Standards of Care, Meeting News
Panel Explores Emerging Treatments and Sequencing Strategies for Patients with Advanced NSCLCs Driven by Rare Oncogenes

During the 2022 European Lung Cancer Congress, experts reviewed evidence on drugs targeting MET exon 14 skipping mutations and RET, HER2, and BRAF alterations. Read more

Evidence Supports Adding Biological, Pathological, and Molecular Assessments to the TNM Lung Cancer Staging System

Beth Fand Incollingo
on: May 24, 2022In: Evolving Standards of Care, Meeting News
Evidence Supports Adding Biological, Pathological, and Molecular Assessments to the TNM Lung Cancer Staging System

A presentation at the 2022 European Lung Cancer Congress convinced attendees that the current system for staging lung cancer needs refinement. Read more


As Treatment Options in Lung Cancer Have Expanded, so Have Costs

Giulia Pasello, MD, PhD
+more
on: May 11, 2022In: Evolving Standards of Care, Patient Advocacy
As Treatment Options in Lung Cancer Have Expanded, so Have Costs

A real-world look at diagnostic-therapeutic pathways explores how they may help provide optimal, innovative care without ballooning costs. Read more

Small, High PLCG2-Expressing Intratumoral Cells May Drive Metastasis

Alvaro Quintanal-Villalonga, PhD
+more
on: May 11, 2022In: Evolving Standards of Care
Small, High PLCG2-Expressing Intratumoral Cells May Drive Metastasis

In the search to understand the mechanisms of metastasis, researchers have expanded the spectrum of SCLC clinical specimens amenable for single-cell resolution analysis. Read more

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