ILCN Lung Cancer News
ILCN Lung Cancer News


  • cfDNA Analysis Suggests EML4-ALK Variant Does Not Influence Response to Lorlatinib

    cfDNA Analysis Suggests EML4-ALK Variant Does Not Influence Response to Lorlatinib

    Meeting News

    By Kara Nyberg, PhD Posted: June 24, 2020 An exploratory analysis of circulating free DNA (cfDNA) shows that lorlatinib confers potent antitumor activity in pretreated patients with ALK-positive NSCLC regardless of EML4-ALK variant type and across a variety of ALK resistance mutations. The duration of response also appears consistent across all ALK fusion subtypes. “Our…