ILCN Lung Cancer News
ILCN Lung Cancer News


  • PD-L1 Testing for Lung Cancer in 2019: Perspective From the IASLC Pathology Committee

    PD-L1 Testing for Lung Cancer in 2019: Perspective From the IASLC Pathology Committee

    Diagnostic Oncology

    By Sylvie Lantuejoul, MD, PhD, and Mari Mino-Kenudson, MD Posted: April 16, 2020 Immune checkpoint inhibitors (ICI), which target the PD-1/PD-L1 axis with the aim of restoring anti-tumor immunity, are now available in routine clinical practice for the treatment of patients with advanced or metastatic NSCLC and SCLC. Several biomarkers have been reported to predict…


  • Tumor Mutation Burden: Evolution of a Controversial Biomarker From the Pathologist’s Perspective

    Tumor Mutation Burden: Evolution of a Controversial Biomarker From the Pathologist’s Perspective

    Diagnostic Oncology

    By Lynette M. Sholl, MD, and John W. Longshore, PhD, FACMG Posted: February 12, 2020 Dr. Lynette M. Sholl Dr. John W. Longshore The profound impact of immunotherapy in patients with lung cancer has been described extensively by many experts within the IASLC.1,2 There are, however, broad disparities in outcomes for patients with lung cancer…


  • PD-L1 in Cytology Specimens

    PD-L1 in Cytology Specimens

    Diagnostic Oncology

    By Anjali Saqi, MD, MBA; Deepali Jain, MD, FIAC; Lukas Bubendorf, MD; Keith Kerr, MB, ChB, MRCPath, FRCPath, FRCP(Ed); and Andre Moreira, MD, PhD Posted: December 11, 2019 Lung cancer is a leading cause of cancer-related deaths worldwide. In the 21st century, there have been two significant developments in the systemic management of lung cancers.…