By Anja C. Roden, MD, and Natasha Rekhtman, MD, PhD Posted: May 27, 2019 Dr. Anja C. Roden Pulmonary neuroendocrine tumors are classified according to the World Health Organization into typical and atypical carcinoid tumors, small cell lung cancer (SCLC), and large cell neuroendocrine carcinomas (LCNEC).1 Whereas typical and atypical carcinoid tumors are considered to be…

By Andre L. Moreira, MD Posted: April 1, 2019 Most of the progress in thoracic oncology is in the treatment of patients with NSCLC. The determination of subtypes of NSCLC, namely adenocarcinoma and squamous cell carcinoma, is directly linked with chemotherapy regimens and the search for targetable molecular alterations. The 2015 World Health Organization Classification of…

By Keith M. Kerr, BSc, MB, ChB, FRCPath, FRCPE Posted: March 1, 2019  There was a time, remembered by us older pathologists, when the image of pathology was that of a rather peripheral specialty, sometimes perceived to have limited clinical relevance, delivered by physicians who were never seen, rarely heard, and were usually banished to some…

By Doreen A. Ezeife, MD, FRCPC; Malcolm Ryan; and Natasha B. Leighl, MD, MMSc, FRCPC, FASCO Posted: March 1, 2019 Dramatic improvements in lung cancer outcomes can be attributed to recent advances in novel targeted therapy and immunotherapy. As the treatment paradigm for lung cancer evolves, concerns about the rising cost of these novel therapeutics…

By Sanja Dacic, MD, PhD, and Douglas J. Hartman, MD Posted: December 2018 The pathology community initially showed resistance to digital pathology implementation in routine practice mostly because of pathologists’ lack of experience with the ever-changing technology, traditional thinking that review of digital images is more time consuming than light microscopy, and lack of approval…