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Home Systemic, Targeted, & Immune Therapies

IMpower133: Finally Moving the Needle in SCLC

on: February 25, 2019In: Systemic, Targeted, & Immune Therapies
IMpower133: Finally Moving the Needle in SCLC

By Stephen V. Liu, MD Posted: March 1, 2019 Dr. Stephen V. Liu The addition of atezolizumab to standard chemotherapy for extensive-stage SCLC achieved what, for decades, had been beyond […] Read more


Dr. Jamie E. Chaft Discusses Emerging Data on Induction Immunotherapy for NSCLC

on: February 25, 2019In: Systemic, Targeted, & Immune Therapies
Dr. Jamie E. Chaft Discusses Emerging Data on Induction Immunotherapy for NSCLC

Posted: March 1, 2019 In the following interview, Jamie E. Chaft, MD, a medical oncologist at the Memorial Sloan Kettering Cancer Center, discusses new data on induction immunotherapy for patients […] Read more

Ongoing Clinical Challenges: Defining Immunotherapy Benefit for Patients With NSCLC and Poor Performance Status

on: February 11, 2019In: Systemic, Targeted, & Immune Therapies
Ongoing Clinical Challenges: Defining Immunotherapy Benefit for Patients With NSCLC and Poor Performance
            Status

This article is the first in a two-part series on ongoing challenges using immunotherapy in special populations. The second part of this series focuses on elderly patients. By Valérie Gounant, MD, and […] Read more

Explaining IMpower132: An Interview with Dr. Vassiliki A. Papadimitrakopoulou

on: December 12, 2018In: Systemic, Targeted, & Immune Therapies
Explaining IMpower132: An Interview with Dr. Vassiliki A. Papadimitrakopoulou

Posted: December 2018 In the following interview, Vassiliki A. Papadimitrakopoulou, MD, Jay and Lori Eisenberg Distinguished Professor of Medicine and section chief of Thoracic Medical Oncology at the University of […] Read more

Targeted Therapy Plus Immune Checkpoint Inhibitors: Research Opportunities, But No Improvement in Activity to Date

on: December 12, 2018In: Systemic, Targeted, & Immune Therapies
Targeted Therapy Plus Immune Checkpoint Inhibitors: Research Opportunities, But No Improvement in
            Activity to Date

By Ross Soo, MB BS, PhD, FRACP Posted: December 2018 The treatment of patients with advanced NSCLC harbouring an actionable oncogene with tyrosine kinase inhibitors (TKIs) directed at its oncogenic […] Read more

Neoadjuvant Nivolumab Shows Unprecedented Pathologic Complete Response for Stage III NSCLC

on: December 12, 2018In: Systemic, Targeted, & Immune Therapies
Neoadjuvant Nivolumab Shows Unprecedented Pathologic Complete Response for Stage III NSCLC

By Mariano Provencio-Pulla, MD, PhD Posted: December 2018 Patients with stage IIIA NSCLC with clinically evident N2 nodal spread have an overall 5-year survival rate of only 10% to 15%. […] Read more

KEYNOTE-042: No Hard and Fast Rules for First-Line Pembrolizumab Regarding PD-L1–Positive Disease

on: August 27, 2018In: Systemic, Targeted, & Immune Therapies
KEYNOTE-042: No Hard and Fast Rules for First-Line Pembrolizumab Regarding PD-L1–Positive
            Disease

By Kara Nyberg, PhD Posted: August 2018 The pace of research focused on new therapies for advanced NSCLC has progressed from a trot to a sprint in recent years. Among […] Read more

Updated Results from the Phase III ALEX Trial: Embracing Hazard Ratios

on: August 27, 2018In: Systemic, Targeted, & Immune Therapies
Updated Results from the Phase III ALEX Trial: Embracing Hazard Ratios

By D. Ross Camidge, MD, and Mary W. Redman, PhD Posted: August 2018 Updates of the primary analysis of the phase III ALEX trial were presented at the American Society […] Read more

Immunotherapy Succeeds in Squamous NSCLC, Establishing a New Frontline Standard of Care

on: August 27, 2018In: Systemic, Targeted, & Immune Therapies
Immunotherapy Succeeds in Squamous NSCLC, Establishing a New Frontline Standard of Care

By Kara Nyberg, PhD Posted: August 2018 Treatment advances for metastatic squamous cell carcinoma have long lagged behind those for other NSCLC subtypes, forcing patients with this difficult-to-treat disease to […] Read more

AACR 2018: First-Line Management of Advanced NSCLC Enters New Era

on: May 31, 2018In: Systemic, Targeted, & Immune Therapies
AACR 2018: First-Line Management of Advanced NSCLC Enters New Era

By Corey Langer, MD, IASLC Lung Cancer News Editor Posted: June 2018 The therapeutic landscape irrevocably altered on April 17, 2018, when three pivotal trials—KEYNOTE 189, CheckMate 227 and Impower […] Read more

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