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Home Archives for June 2024

CROWN Results Demonstrate Longest Progression-Free Survival in Advanced NSCLC Seen to Date

Erin Jungmeyer
on: June 25, 2024In: Evolving Standards of Care, Meeting News
CROWN Results Demonstrate Longest Progression-Free Survival in Advanced NSCLC Seen to Date

When presenting the data, Dr. Benjamin Solomon said first-line lorlatinib offers unprecedented improvement in outcomes for patients with advanced ALK+ non-small cell lung cancer. Read more


Subcutaneous Amivantamab Leads to Unexpected OS Improvement vs. IV Dosing in Refractory, EGFR+ Advanced NSCLC

Fred Gebhart
on: June 25, 2024In: Evolving Standards of Care, Meeting News
Subcutaneous Amivantamab Leads to Unexpected OS Improvement vs. IV Dosing in Refractory, EGFR+ Advanced NSCLC

Dr. Natasha Leighl said the findings of PALOMA-3 show subcutaneous dosing offers other advantages, including reduced adverse events. Read more

KRYSTAL-12 Supports Previous Evidence Showing Adagrasib is Superior to Docetaxel in Pretreated Advanced KRAS-mutated NSCLC

Fred Gebhart
on: June 25, 2024In: Evolving Standards of Care, Meeting News
KRYSTAL-12 Supports Previous Evidence Showing Adagrasib is Superior to Docetaxel in Pretreated Advanced KRAS-mutated NSCLC

Dr. Tony Mok said the results of the phase III KRYSTAL-12 trial reinforce adagrasib as an effective second-line treatment option for this patient population. Read more

Cytisine: A New Opportunity in the UK for the Treatment of Tobacco Dependency

Joelle Fathi, DNP, RN, ARNP, CTTS, FAANP, FAAN
+more
on: June 25, 2024In: Tobacco Control & Smoking Cessation
Cytisine: A New Opportunity in the UK for the Treatment of Tobacco Dependency

Drs. Joelle Fathi and Matt Evision say cytisine more than doubles the chance of cessation and its expanding accessibility heralds a new era in the management of tobacco dependency. Read more

Recently Reported Evidence Leads to Approvals for Alectinib, Osimertinib

Erin Jungmeyer
on: June 25, 2024In: Industry News & Regulatory Approvals
Recently Reported Evidence Leads to Approvals for Alectinib, Osimertinib

The European Commission has approved adjuvant alectinib for ALK+ early-stage NSCLC while the US FDA has granted priority review for osimertinib for unresectable stage III EGFR+ NSCLC. Read more

LAURA Trial Defines Role of EGFR-directed Therapy in Unresectable Stage III NSCLC

Erin Jungmeyer
on: June 11, 2024In: Evolving Standards of Care, Meeting News
LAURA Trial Defines Role of EGFR-directed Therapy in Unresectable Stage III NSCLC

Primary results from the study, presented by Dr. Suresh Ramalingam, showed osimertinib offers a significant improvement in progression-free survival following chemoradiotherapy. Read more

ADRIATIC Demonstrates Meaningful Improvements in OS, PFS in Patients with Limited-stage SCLC

Erin Jungmeyer
on: June 11, 2024In: Evolving Standards of Care, Meeting News
ADRIATIC Demonstrates Meaningful Improvements in OS, PFS in Patients with Limited-stage SCLC

As the first study to establish the role of immunotherapy in this setting, Dr. David R. Spigel says consolidation durvalumab will become the new standard of care for this population. Read more

Patient Perspective: Exercise Prescriptions Needed for Lung Cancer Patients

Angus Pratt, MBA
on: June 11, 2024In: Patient Advocacy
Patient Perspective: Exercise Prescriptions Needed for Lung Cancer Patients

Runner and patient advocate Angus Pratt says running three times a week may be the antithesis of what most people expect from a lung cancer patient, but not only is it possible, it is beneficial. Read more

Glecirasib Shows Promise in Treating Advanced Lung Cancer Harboring KRAS G12C Mutations

Erin Jungmeyer
on: June 11, 2024In: Evolving Standards of Care
Glecirasib Shows Promise in Treating Advanced Lung Cancer Harboring KRAS G12C Mutations

With only 5% of patients stopping treatment due to treatment-related adverse events, lead author Yuankai Shi, MD, says glecirasib may help improve patient compliance with oral therapy. Read more

US FDA Grants Accelerated Approval to Tarlatamab-dlle for Extensive-stage Small Cell Lung Cancer

Erin Jungmeyer
on: June 11, 2024In: Industry News & Regulatory Approvals
US FDA Grants Accelerated Approval to Tarlatamab-dlle for Extensive-stage Small Cell Lung Cancer

The first-in-class immunotherapy offers a new option for SCLC patients with disease progression on or after platinum-based chemotherapy. Read more

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MARIPOSA OS Data Confirms Improved Efficacy for Amivantamab Plus Lazertinib in the First Line for EGFR-mutated NSCLC

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COCOON’s Prophylactic Regimen Resulted in Decreased Incidence and Severity of Dermatologic-related Adverse Events

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Discussion Covered Updates, Strategies, and Controversies in Lung Cancer Staging
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Treatment of Immunotherapy-Related Dermatologic Toxicities: An Interview with Dr. Mario Lacouture
WCLC Attendees Hear Preview of Proposed Changes for the 9th Edition of the TNM Staging Classification for Thoracic Cancers
Potential Impact of GLP1-RAs on TKI-induced Weight Gain in Patients with NSCLC
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