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Home Archives for 2024

Investigators Report Efficacy, Safety Analysis of Tarlatamab in SCLC Patients With or Without Baseline Brain Metastases

John Austin
on: July 09, 2024In: Evolving Standards of Care, Meeting News
Investigators Report Efficacy, Safety Analysis of Tarlatamab in SCLC Patients With or Without Baseline Brain Metastases

Dr. Anne-Marie C. Dingemans said the data indicate that it is safe to prescribe tarlatamab for these patients now that it has been approved by the US FDA. Read more


Data Look Promising for First-line Sotorasib, Platinum-based Chemotherapy Combination for KRAS-mutant NSCLC

Fred Gebhart
on: July 09, 2024In: Evolving Standards of Care, Meeting News
Data Look Promising for First-line Sotorasib, Platinum-based Chemotherapy Combination for KRAS-mutant NSCLC

Presenter Dr. Bob T. Li said further study is needed, particularly given the positive PFS results in PDL-1-negative patients, who represent an unmet medical need. Read more

Osimertinib Plus Chemotherapy May Improve CNS Activity in Advanced EGFR-positive NSCLC

Marthe S. Paats, MD, PhD
+more
on: July 09, 2024In: Evolving Standards of Care
Osimertinib Plus Chemotherapy May Improve CNS Activity in Advanced EGFR-positive NSCLC

However, Drs. Marthe S. Paats and Anne-Marie C. Dingemans caution that in the light of the toxicity profile, the combination may not be the best option for all patients. Read more

Journal of Thoracic Oncology’s Impact Factor Rises Again; JTO Clinical and Research Reports Receives First Impact Factor

Erin Jungmeyer
on: July 09, 2024In: Society News
Journal of Thoracic Oncology’s Impact Factor Rises Again; JTO Clinical and Research Reports Receives First Impact Factor

The IASLC’s official journal now ranks second among 100 respiratory medicine journals and 13th among 322 oncology journals. Read more

CROWN Results Demonstrate Longest Progression-Free Survival in Advanced NSCLC Seen to Date

Erin Jungmeyer
on: June 25, 2024In: Evolving Standards of Care, Meeting News
CROWN Results Demonstrate Longest Progression-Free Survival in Advanced NSCLC Seen to Date

When presenting the data, Dr. Benjamin Solomon said first-line lorlatinib offers unprecedented improvement in outcomes for patients with advanced ALK+ non-small cell lung cancer. Read more

Subcutaneous Amivantamab Leads to Unexpected OS Improvement vs. IV Dosing in Refractory, EGFR+ Advanced NSCLC

Fred Gebhart
on: June 25, 2024In: Evolving Standards of Care, Meeting News
Subcutaneous Amivantamab Leads to Unexpected OS Improvement vs. IV Dosing in Refractory, EGFR+ Advanced NSCLC

Dr. Natasha Leighl said the findings of PALOMA-3 show subcutaneous dosing offers other advantages, including reduced adverse events. Read more

KRYSTAL-12 Supports Previous Evidence Showing Adagrasib is Superior to Docetaxel in Pretreated Advanced KRAS-mutated NSCLC

Fred Gebhart
on: June 25, 2024In: Evolving Standards of Care, Meeting News
KRYSTAL-12 Supports Previous Evidence Showing Adagrasib is Superior to Docetaxel in Pretreated Advanced KRAS-mutated NSCLC

Dr. Tony Mok said the results of the phase III KRYSTAL-12 trial reinforce adagrasib as an effective second-line treatment option for this patient population. Read more

Cytisine: A New Opportunity in the UK for the Treatment of Tobacco Dependency

Joelle Fathi, DNP, RN, ARNP, CTTS, FAANP, FAAN
+more
on: June 25, 2024In: Tobacco Control & Smoking Cessation
Cytisine: A New Opportunity in the UK for the Treatment of Tobacco Dependency

Drs. Joelle Fathi and Matt Evision say cytisine more than doubles the chance of cessation and its expanding accessibility heralds a new era in the management of tobacco dependency. Read more

Recently Reported Evidence Leads to Approvals for Alectinib, Osimertinib

Erin Jungmeyer
on: June 25, 2024In: Industry News & Regulatory Approvals
Recently Reported Evidence Leads to Approvals for Alectinib, Osimertinib

The European Commission has approved adjuvant alectinib for ALK+ early-stage NSCLC while the US FDA has granted priority review for osimertinib for unresectable stage III EGFR+ NSCLC. Read more

LAURA Trial Defines Role of EGFR-directed Therapy in Unresectable Stage III NSCLC

Erin Jungmeyer
on: June 11, 2024In: Evolving Standards of Care, Meeting News
LAURA Trial Defines Role of EGFR-directed Therapy in Unresectable Stage III NSCLC

Primary results from the study, presented by Dr. Suresh Ramalingam, showed osimertinib offers a significant improvement in progression-free survival following chemoradiotherapy. Read more

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