Timely and relevant thoracic oncology news brought to you by the only global association dedicated to the multidisciplinary study of lung cancer.

Timely and relevant thoracic oncology news brought to you by the only global association dedicated to the multidisciplinary study of lung cancer.


Evolving Standards of Care


  • From Access to Eligibility: What Poland’s Real-World Stage III NSCLC Data Reveal About Treatment Pathways and Health Policy

    From Access to Eligibility: What Poland’s Real-World Stage III NSCLC Data Reveal About Treatment Pathways and Health Policy

    By

    Łukasz Kuncman, MD, PhD, DSc
    Diagnostic Oncology, Evolving Standards of Care

    Dr. Łukasz Kuncman expands on findings from a multicenter Polish study analyzing referral patterns and clinical practice in patients with unresectable stage III NSCLC, emphasizing that access to the modern standard of care depends on a chain of eligibility.


  • Opti-TROP Lung 05 Trial Results Expand First-Line Treatment Options for PD-L1-Positive Advanced NSCLC

    Opti-TROP Lung 05 Trial Results Expand First-Line Treatment Options for PD-L1-Positive Advanced NSCLC

    By

    Haleigh Behrman
    Evolving Standards of Care, Meeting News, Targeted Therapies

    Dr. Caicun Zhou indicated that treatment with sac-TMT plus pembrolizumab demonstrated a clinically meaningful PFS benefit and favorable OS trends compared with pembrolizumab monotherapy.


  • Wu-Kong28 Data Support Sunvozertinib as First-Line Treatment Option for EGFR-Mutant NSCLC, Researcher Says

    Wu-Kong28 Data Support Sunvozertinib as First-Line Treatment Option for EGFR-Mutant NSCLC, Researcher Says

    By

    Haleigh Behrman
    Evolving Standards of Care, Meeting News, Targeted Therapies

    Sunvozertinib demonstrated significantly superior anti-tumor efficacy versus chemotherapy, along with a manageable safety profile and potential long-term survival benefits, according to new data presented by Dr. John V. Heymach.


  • Successive Translations of the Same Target: Highlights from ASCO 2026

    Successive Translations of the Same Target: Highlights from ASCO 2026

    By

    Gilberto de Lima Lopes Junior, MD, MBA, FASCO
    Evolving Standards of Care, Meeting News

    In the first half of a two-part editorial, Dr. Gilberto Lopes translates breaking data from several trials that made headlines at ASCO 2026.


  • Toward Durable Disease Control in EGFR-Mutant (mt) NSCLC: Interpreting the Survival Signals from FLAURA2 and MARIPOSA

    Toward Durable Disease Control in EGFR-Mutant (mt) NSCLC: Interpreting the Survival Signals from FLAURA2 and MARIPOSA

    By

    Ilit Turgeman, MD, et al.
    Evolving Standards of Care, Targeted Therapies

    While the FLAURA2 and MARIPOSA trials represent a defining step toward durable disease control in EGFR mt (+) NSCLC, Drs. Ilit Turgeman and Pasi A. Jänne emphasize that further advances will depend on understanding what persists after an initial response.


  • HARMONi-6 Trial Results Show Consistent OS Benefit Across Key Subgroups

    HARMONi-6 Trial Results Show Consistent OS Benefit Across Key Subgroups

    By

    Haleigh Behrman
    Evolving Standards of Care, Meeting News

    Dr. Shun Lu, who presented the findings during the main plenary session at the 2026 ASCO Annual Meeting, said the results support adopting ivonescimab plus chemotherapy as a potential new standard of care for advanced squamous NSCLC.


  • Asandeutertinib Goes Head-to-Head With Osimertinib in Phase II ESAONA Trial

    Asandeutertinib Goes Head-to-Head With Osimertinib in Phase II ESAONA Trial

    By

    Haleigh Behrman
    Evolving Standards of Care, Meeting News

    Interim results from the ESAONA trial, presented by Dr. Yuankai Shi, revealed that asandeutertinib demonstrated significant improvements in iORR and iPFS versus osimertinib for EGFR-mutant NSCLC with brain metastases.


  • Knowing Before We Can Act: The Value of MRD Testing From a Patient’s Perspective

    Knowing Before We Can Act: The Value of MRD Testing From a Patient’s Perspective

    By

    Jan Pezarro
    Evolving Standards of Care, Patient Advocacy & Survivorship

    While MRD testing does not eliminate the uncertainty of recurrence, Jan Pezarro explains how advanced molecular testing provides invaluable clarity for patients.


  • What Do Recent ODAC Decisions Mean for Lung Cancer Drug Development and Clinical Trial Design?

    What Do Recent ODAC Decisions Mean for Lung Cancer Drug Development and Clinical Trial Design?

    By

    Haleigh Behrman
    Clinical Trial Design, Evolving Standards of Care

    In a Q&A with ILCN, Dr. John V. Heymach addresses several rulings from the Oncologic Drugs Advisory Committee and important lessons for research teams.


  • Investigational KRAS G12D Agents Demonstrate Promising Antitumor Activity in Non-Small Cell Lung Cancer

    Investigational KRAS G12D Agents Demonstrate Promising Antitumor Activity in Non-Small Cell Lung Cancer

    By

    Taylor Fithian
    Evolving Standards of Care, Industry News & Regulatory Approvals

    Early findings from two clinical studies support the continued development of setidegrasib and zoldonrasib to target KRAS G12D mutations.