Overcoming Resistance Remains a Challenge in Targeting KRAS
Haleigh BehrmanDana-Farber's Dr. Alice Shaw recently explored various combination strategies that show promise in preventing or delaying resistance in this previously undruggable space. Read more
Immune Checkpoint Inhibitors in NSCLC: Do Survival Benefits End if Treatment Does?
Haleigh BehrmanDrs. Mark Awad and Federica Pecci said recent findings suggest some patients with non-small cell lung cancer may experience survival benefits and disease control even after stopping ICI treatment. Read more
Research to Watch: CAN-2409 Demonstrates Survival Benefit in Patients with Advanced NSCLC Unresponsive to ICIs
Haleigh BehrmanAccording to recent phase II data, the experimental treatment demonstrated a median overall survival of 24.5 months. Read more
The US FDA grants accelerated approval to telisotuzumab vedotin-tllv for advanced NSCLC with high c-Met overexpression. Read more
Pembrolizumab-chemotherapy combo receives Canadian approval for first-line treatment of malignant pleural mesothelioma. Read more
A 40-Year Chase in SCLC: Where We’ve Been and Where We’re Going
Haleigh BehrmanPioneer in SCLC research Dr. John D. Minna reflected on four decades of advancements in the field during his keynote address at the 2025 Hot Topics in SCLC. Read more
Results From the AENEAS2 Trial Point to a New Frontline Treatment Option for NSCLC
Nathan PettengillResearch team led by Dr. Shun Lu presents aumolertinib with chemotherapy as an additional first-line treatment option during the 2025 AACR Annual Meeting. Read more
Beamion LUNG-01 Trial Results Support Zongertinib’s Potential as a First-Line Therapy
Haleigh BehrmanDr. John V. Heymach says the latest findings suggest zongertinib may address an unmet need for patients with HER2-mutant NSCLC. Read more
A Real Tail in These Curves: A Look at Advances and Future Directions in SCLC
Haleigh BehrmanDuring a recent address at SCLC 2025, Dr. Charles Rudin discussed the progress being made in reducing the incidence of small cell lung cancer and in treating it. Read more
COCOON Regimen Demonstrates Improvement in Dermatologic Toxicities
Nathan PettengillDr. Nicolas Girard recently presented data that shows prophylactic treatment with oral and topical antibiotics and ceramide-based moisturizer significantly reduced adverse skin events. Read more