A Real Tail in These Curves: A Look at Advances and Future Directions in SCLC
Haleigh BehrmanDuring a recent address at SCLC 2025, Dr. Charles Rudin discussed the progress being made in reducing the incidence of small cell lung cancer and in treating it. Read more
COCOON Regimen Demonstrates Improvement in Dermatologic Toxicities
Nathan PettengillDr. Nicolas Girard recently presented data that shows prophylactic treatment with oral and topical antibiotics and ceramide-based moisturizer significantly reduced adverse skin events. Read more
Savolitinib Plus Osimertinib Offers Hope for Addressing Resistance, Progression
Nathan PettengillDr. Myung-Ju Ahn said recent data from SAVANNAH show the combination produced a meaningful and durable response in patients whose cancer progressed after osimertinib. Read more
Final MARIPOSA Analysis Confirms OS Improvement Versus Osimertinib Monotherapy
Haleigh BehrmanDrs. Chih-Hsin Yang and Pérol reviewed the latest findings and key takeaways during a presentation at the European Lung Cancer Congress. Read more
Pathology Researcher Keith Kerr Receives 2025 Heine H. Hansen Award
Nathan PettengillDuring his award lecture at the European Lung Cancer Congress, Dr. Kerr said lung cancer treatment has benefited from the bridging of the historical divide between pathology and medical oncology. Read more
Foritinib Gains Momentum in China for ALK-positive NSCLC
Haleigh BehrmanChina’s NMPA accepts a marketing authorization application for foritinib following interim results from the phase III REMARK trial. Read more
Potential Impact of GLP1-RAs on TKI-induced Weight Gain in Patients with NSCLC
Maaike van den Bos, MD+more
Anti-obesity medications could theoretically reduce the absorption of oral TKIs, particularly in cases of lipophilicity, where therapeutic agents have a strong dependence on dietary fat for adequate dissolution. Read more
Zipalertinib Meets Primary Endpoint in Phase 2b Trial
Nathan PettengillThe drug’s developers have said the data show a positive overall response rate in previously treated patients with NSCLC with EGFR exon 20 insertion mutations. Read more
Will Bispecific Antibodies Replace PD-(L)1 Targeted Agents?
Nathan PettengillDrs. Jonathan W. Riess and Greg Kalemkerian present opposing views regarding the therapeutic potential of novel targeted therapies. Read more
Debate Leaves Audience Unconvinced that KRAS Inhibitors Deserve Promotion to First-Line Treatment
Nathan PettengillWhile Dr. Trever Bivona argued that KRAS inhibitors will join other seminal oncogene inhibitors, Dr. Rebecca Heist said the data has yet to demonstrate they outperform the current second-line standard of care. Read more