Timely and relevant thoracic oncology news brought to you by the only global association dedicated to the multidisciplinary study of lung cancer.

Timely and relevant thoracic oncology news brought to you by the only global association dedicated to the multidisciplinary study of lung cancer.



  • In Brief: July 23, 2025

    In Brief: July 23, 2025

    By

    Haleigh Behrman
    Industry News & Regulatory Approvals, Society News

    The US FDA grants Orphan Drug Designation to CID-078 for SCLC, and zidesamtinib demonstrates positive early data in ROS1-positive NSCLC.


  • SACHI Trial Results: Savolitinib-Osimertinib Combo Improves PFS in MET-Amplified EGFR-Mutated NSCLC

    SACHI Trial Results: Savolitinib-Osimertinib Combo Improves PFS in MET-Amplified EGFR-Mutated NSCLC

    By

    Haleigh Behrman
    Evolving Standards of Care, Meeting News, Society News

    Dr. Shun Lu said savolitinib plus osimertinib offers a potential new chemo-free treatment option for patients after progression on first-line treatment.


  • IMpower010 Trial Update Highlights Long-Term Benefits of Adjuvant Atezolizumab in Resected NSCLC

    IMpower010 Trial Update Highlights Long-Term Benefits of Adjuvant Atezolizumab in Resected NSCLC

    By

    Haleigh Behrman
    Evolving Standards of Care, Meeting News, Society News

    The updated data and a recently presented exploratory analysis show the benefits varied based on PD-L1 expression, which may be influenced by a variety of genomic alterations.


  • In Brief for July 9, 2025

    In Brief for July 9, 2025

    By

    Haleigh Behrman
    Industry News & Regulatory Approvals, Society News

    The FDA grants accelerated approval to Dato-DXd, while a Biologics License Application for HER3-DXd is voluntarily withdrawn.


  • Tarlatamab Emerges as New Standard of Care in Second-Line SCLC, with Significant Gains in OS, PFS

    Tarlatamab Emerges as New Standard of Care in Second-Line SCLC, with Significant Gains in OS, PFS

    By

    Joy Curzio
    Evolving Standards of Care, Meeting News, Society News

    Dr. Charles M. Rudin, who presented data from the DeLLphi-304 trial at ASCO 2025, noted that patient-reported outcomes also showed improvements in common symptoms, including dyspnea and cough, with fewer toxicities of grade 3 or higher.


  • A Paradigm Shift: Final 5-Year Overall Survival Results from CheckMate 816 in Resectable NSCLC

    A Paradigm Shift: Final 5-Year Overall Survival Results from CheckMate 816 in Resectable NSCLC

    By

    Haleigh Behrman
    Evolving Standards of Care, Meeting News, Society News

    Dr. Patrick Forde recently presented milestone data from the trial that confirms the benefit of neoadjuvant-only chemoimmunotherapy for the treatment of resectable lung cancer.


  • Research to Watch: FDA Grants ZL-1310 Fast Track Designation for Extensive-Stage SCLC

    Research to Watch: FDA Grants ZL-1310 Fast Track Designation for Extensive-Stage SCLC

    By

    Haleigh Behrman
    Industry News & Regulatory Approvals, Society News

    ZL-1310 earns Fast Track Designation as a potential first-in-class DLL3-targeted ADC for extensive-stage small cell lung cancer.


  • In Brief for June 25, 2025

    In Brief for June 25, 2025

    By

    Haleigh Behrman
    Industry News & Regulatory Approvals, Society News

    The US FDA recently granted approval to taletrectinib for ROS1-positive NSCLC and accepted a priority review for lurbinectedin plus atezolizumab for ES-SCLC in the first-line setting.


  • Lurbinectedin and Atezolizumab Combo Demonstrates Survival Benefit in ES-SCLC

    Lurbinectedin and Atezolizumab Combo Demonstrates Survival Benefit in ES-SCLC

    By

    Haleigh Behrman
    Meeting News, Society News

    Dr. Luis G. Paz-Ares reviewed new IMforte trial results at the 2025 ASCO Annual Meeting.


  • Early Data Suggest that a 14-Gene Molecular Assay May Help Predict Recurrence Risk in Patients with Early-Stage Non-Squamous NSCLC

    Early Data Suggest that a 14-Gene Molecular Assay May Help Predict Recurrence Risk in Patients with Early-Stage Non-Squamous NSCLC

    By

    Haleigh Behrman
    Meeting News, Society News

    Author Dr. David Spigel says these findings may pave the way for more accurate, biomarker-guided decisions for lung cancer treatment after surgery.