Leveraging Lung Cancer Screening Scans to Detect Early Interstitial and Obstructive Lung Disease
Kara Nyberg, PhDCT screening for lung cancer can reveal subtle early signs of disease in the lungs that extend beyond potential malignancy. As reviewed by Bram van Ginneken, PhD, of the Radboud […] Read more
Low-Dose CT Screening with Guidance from Biomarkers May be Beneficial for Some Patients Who Have Never Smoked
Beth Fand IncollingoAlthough about 20% of those who die of lung cancer in the United States each year have never smoked,1 only individuals with heavy smoking histories are eligible for low-dose CT […] Read more
Strategies for Implementing Lung Cancer Screening Programs in Low-Middle Income Countries
Kara Nyberg, PhDA wide range of nations at various stages of economic and health-system development fall under the umbrella of low- and middle-income countries (LIMC). As Lucía Viola, MD, of the Fundación […] Read more
Low-Dose CT Could be One-Stop Test for Early Signs of China’s ‘Big Three’ Chest Diseases
Finding one effective test for the three chest conditions that are the leading causes of death in China, without a high risk of false positives, would allow better control of […] Read more
The first forays into lung cancer screening began in the 1970s, with two trials evaluating the use of chest x-ray and sputum cytology to detect disease. Those trials showed no […] Read more
Even the most advanced CT scanners available face limitations in their ability to measure small lung nodules. This is a concern since small errors in two-dimensional measures can quickly balloon […] Read more
Prolonging CT Screening Intervals is Deemed Safe in Individuals with Negative Baseline Results
In his May 7 presentation “Advance Lung Cancer Screening Globally,” Dr. Pastorino, co-chair of the CT Screening Symposium and director of the Thoracic Surgery Division at the Istituto Nazionale Tumori in Milan, discussed the MILD, BioMILD, and SMILE trials. He also is chair of the IASLC’s Screening and... Read more
A National Network Provides a Window into Lung Cancer Screening Trends, Successes across the United States
Joy CurzioNow that the positive impact of lung cancer screening on mortality and morbidity is irrefutable, there is an obvious need to find new ways to overcome consistent challenges with implementation […] Read more
Olaparib Maintenance Did Not Improve PFS, OS in Platinum-Sensitive NSCLC
Leah LawrenceThe PARP inhibitor olaparib did not improve PFS or OS compared with placebo when used as a maintenance therapy for patients with platinum-sensitive NSCLC, according to results of the phase […] Read more
CheckMate 9LA Combination Effective in Advanced NSCLC Despite PD-L1 Expression, TMB Status
Leah LawrenceA higher tumor mutational burden (TMB) was associated with improved PFS and overall response rate for patients with advanced NSCLC treated with nivolumab plus ipilimumab plus chemotherapy compared with chemotherapy […] Read more