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Interim NADIM ADJUVANT Data Suggest Adjuvant Chemo-IO May Reduce Recurrence Risk in Patients Following Complete Resection
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Final FLAURA2 OS Data Show Osimertinib Plus Chemo Offers Benefit Compared with Monotherapy
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Potential Impact of GLP1-RAs on TKI-induced Weight Gain in Patients with NSCLC
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No “Known” Risk Factors: The Health Consequences of Radiation Therapy
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Discussion Covered Updates, Strategies, and Controversies in Lung Cancer Staging
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No PFS, OS Benefit Seen in Final Results from PACIFIC-2
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WCLC Attendees Hear Preview of Proposed Changes for the 9th Edition of the TNM Staging Classification for Thoracic Cancers
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Treatment of Immunotherapy-Related Dermatologic Toxicities: An Interview with Dr. Mario Lacouture
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A Holistic Approach to Patient Care
Presidential Symposium
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EA5181 Confirms Durvalumab After CRT is SOC for Unresectable Stage III NSCLC
Dr. John Varlotto highlighted that the survival curves were ‘superimposable,’ showing no differences in median OS or PFS outcomes.
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Nivolumab Boosted Survival in Relapsed Mesothelioma
Nivolumab significantly improved investigator-reported progression-free survival and overall survival compared with placebo in patients with relapsed malignant mesothelioma, according to preliminary results of the CONFIRM phase III trial presented during the Presidential Symposium. “Nivolumab is a safe and effective treatment and should be considered a new treatment option for patients with relapsed mesothelioma,” said Dean…
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KEYNOTE-598: Dual PD-1 and CTLA-4 Checkpoint Blockade Confers No Therapeutic Benefit Beyond PD-1 Blockade Alone in PD-L1–Positive NSCLC
Patients with metastatic NSCLC with a PD-L1 tumor proportion score (TPS) ≥ 50% face greater toxicity without the benefit of enhanced efficacy when ipilimumab is combined with pembrolizumab in the first-line setting, according to findings of the phase III KEYNOTE-598 trial. In fact, the results at the first interim analysis for the immunotherapy combination were…
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LCMC3 Findings Indicate Neoadjuvant Atezolizumab Safe, Efficacious in Resectable Stage IB-IIIB NSCLC
Primary results of the phase II Lung Cancer Mutation Consortium (LCMC) 3 clinical trial suggest that neoadjuvant atezolizumab may be a worthwhile treatment option for selected patients with resectable stage IB-IIIB NSCLC (Abstract PS01.05). Not only did 21% of patients lacking EGFR or ALK genetic aberrations attain a major pathologic response (MPR) at the time…
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Genetically Tailored Treatment Approach Did Not Improve Survival in Stage II-III NSCLC
Evaluation of mRNA expression of selected genes to tailor adjuvant chemotherapy did not improve survival outcomes in patients with resected stage II-III NSCLC, according to results of the ITACA study, presented during the Presidential Symposium. “Despite its modest survival advantages cisplatin-based chemotherapy is considered the standard of care for early-stage completely resected non-small cell lung…