Exploratory IMpower010 Analysis Shows Surgery Type Associated with Favorable DFS, OS Results
Alessandro Brunelli, MD+more
In stage II-IIIA NSCLC patients with high PD-L1 expression, the benefits of atezolizumab and platinum-based chemotherapy after surgical resection appeared to be most prominent in the lobectomy subgroup according to Dr. Alessandro Brunelli and colleagues. Read more
Tumor Treating Fields May Provide Additional Treatment Option for mNSCLC Following Progression
Erin JungmeyerInvestigator Ticiana Leal, MD, said the the phase III LUNAR study met its primary endpoint and demonstrated a statistically significant 3-month improvement in median overall survival versus the standard of care. Read more
ADAURA Demonstrates OS Benefit with Adjuvant Osimertinib in Resectable EGFRm NSCLC
Erin JungmeyerDr. Roy Herbst said the results reinforce adjuvant osimertinib as the standard of care for patients with resected, EGFR-mutated stage IB-IIIA non-small cell lung cancer and highlight the importance of early biomarker testing. Read more
Data Supporting IO Before Surgery in Resectable NSCLC Grows
Erin JungmeyerDuring ASCO’s 2023 Annual Meeting investigators shared findings from several neoadjuvant studies, including KEYNOTE-671 and Neotorch, which showed improved EFS with pembrolizumab and toripalimab, respectively. Read more
From the Editors: Defining Resectability of Non-Small Cell Lung Cancer in 2023
Witold K. Rzyman, MD, PhD+more
Is “resectability” based on radical resection criteria still valid in the era of neoadjuvant immunochemotherapy? ILCN’s editors say the term needs to be revisited and probably redefined based on a tumor’s status before treatment and after neoadjuvant treatment. Read more
ELCC Session Offers Surgical Perspective in Context of Neoadjuvant Immunotherapy
Erin JungmeyerPresenter Dr. Alex Brunelli says neoadjuvant chemoimmunotherapy is a promising and well-tolerated treatment option in select patients with stage III NSCLC. Read more
Radiation Oncologist Makes Case for Radiotherapy for Local Treatment of Select Patients
Erin JungmeyerCan radiotherapy replace surgery in stage III NSCLC in the era of immunotherapy? During ELCC 23, Dr. Sara Ramella turned to the data to answer that question. Read more
Health Canada gives greenlight to cemiplimab-chemo combo for first-line treatment of advanced NSCLC. Early registration for WCLC 23 ends June 9. Read more
Amivantamab Demonstrates Consistent Efficacy in CHRYSALIS Follow-up
Erin JungmeyerSpain’s Dr. Pilar Garrido reviews long-term efficacy, safety, and predictors-of-response data for post-platinum advanced NSCLC patients with EGFR exon 20 insertion mutations. Read more
Early Detection Researcher Shares Epidemiologic Evidence on Air Pollution, Lung Cancer
Erin JungmeyerDr. Christine Berg says both smoking and air pollution are important in causing lung cancer. And both need to be eliminated to help prevent it and save lives. Read more