TKI Plus Checkpoint Inhibitor Without Chemotherapy Shows Promise as Initial Option in Advanced NSCLC
Beth Fand IncollingoThe combination of an anti-angiogenic tyrosine kinase inhibitor (TKI) and an anti-PD-1 immunotherapy proved promising, regardless of PD-L1 expression levels, as a first-line therapy for treatment-naïve patients with advanced NSCLC […] Read more
Co-mutations in DNA Damage-Response Pathways May Predict Effectiveness of Checkpoint Inhibitors in NSCLC
Beth Fand IncollingoNSCLC that harbors more than one DNA damage-response (DDR) gene alteration is more likely to respond to immunotherapy than disease that harbors one or no such mutations. So concluded investigators […] Read more
A significant number of patients with lung cancer did not undergo testing for all relevant biomarkers, according to real-world data from a study in Japan (MA08.08), and use of simultaneous […] Read more
Management of Long-Term Immune-Related Toxicities Needed in NSCLC
Beth Fand IncollingoWhile checkpoint inhibitors have improved the outlook for patients with advanced NSCLC, more information is needed about the long-term toxicities caused by the drugs and how they should be managed. […] Read more
Raising Awareness about Lung Cancer Screening among Minorities, People Who Smoke
Dusty DonaldsonMinorities are at significantly higher risk for developing lung cancer than whites, even with the same smoking history. In an attempt to, in part, address this disparity, the U.S. Preventive […] Read more
Additional ADAURA Analyses Help Support the Benefit of Adjuvant Osimertinib in Patients With Resected EGFR-Mutated NSCLC
Kara Nyberg, PhDThe randomized phase III ADAURA trial stirred up considerable excitement last year when results from an unplanned interim analysis revealed an 80% reduction in the risk of disease recurrence or […] Read more
Lung Cancer Screening for Women: Understanding the Risks and the Benefits
Dusty DonaldsonAlthough science has proven that both men and women significantly benefit from lung cancer screening by low-dose CT, the NELSON study showed that women benefit substantially more than men.1 However, […] Read more
Becoming a Critical Actor—Learning about Improving Equity and Inclusion in the Workplace
The recent Women in Thoracic Oncology Networking Event provided its audience with the rare opportunity to speak openly and honestly about challenges in the workforce, from microaggressions to wage gaps […] Read more
LGBT Cancer Survivors and Disparities-Related Barriers That May Affect Survival
Beth Fand IncollingoCancer survivors who are lesbian, gay, bisexual, or transgender (LGBT) face potentially survival-limiting health disparities, and this should be addressed by the healthcare system. Those were the findings of a […] Read more
Distressed Due to Pandemic, Patients with Lung Cancer Seek Educational Resources
Beth Fand IncollingoA Canadian survey conducted repeatedly throughout the COVID-19 pandemic reflects a rise in feelings of isolation and vulnerability among patients with lung cancer. Survey results indicate that patients want educational […] Read more